My opinion depends on what you want your sand bed to do. If you're looking for nitrifying filtration, detritus cleanup, and food production then I's suggest 1/2" - 1".
If you want the above plus denitrification I'd suggest at least 3"; more if you stock fish heavily.
hey Guy, i have about 100 to 110lbs. of live sand in my 150. I also have a red coris wrasse, formosion wrasse, chisletooth wrasse and a dragon wrasse which all sleep in the sand. i also have a bullet goby. The questions are can i add the play sand from home depot and will it become live sand after while? I dont think i have enough sand, not that i need a lot, but the dragon is making a mound of a nest in the back with the sand and the various loose rocks i have.
thanks for your time 8)
If your current sand is live then the new sand will quickly become live sand. Just don't add more than 1/2" at a time to allow the criters to form new tunnels. 1/2" a week is a good rate to add sand IMO.