I wish I had more concrete absolute definitive rules regarding potassium I could share, but overtime, in various reef system, with various water sources (natural, vs brand a ASW, vs brand ASW), supplement regimes and such.
I recommend any change in addtive regime should be done one at a time, especially if it is a hard to test, and variably interactive element or compound such we see quite readily with iron and potassium.
We have some pretty good safe rules for alkalinity and calcium, which are easy to test, and concentration effects, and reliable effects noted. We know a lot about the interplay between alk and calcium concentrations, and their direct effects on each others concentration, as well as Magnesium's effect on changing the all/ca solubility sea saw, allowing more calcium to remain in solution at a given alk unity. There are many of these interactions of all the various ions in saltwater, all affecting each other to varying degrees.
I really do think testing is great, and I can't disparage the "don't add what you can't test for" rule. But... We won't be seeing a quick and accurate iron test any time soon, it is known that iron reacts very quickly in seawater, within half an hour 99% of iron added may no longer be in solution, having reacted with other ions in the system and uptake from animals. Natural levels are usually in the parts per billion. Minutes after a dose (ideally I drop dose over the course of the day) concentrations could be 100s of times higher than natural sea water. If we did that with other ions it would be catastrophe. I know if I don't dose iron my coral don't look as good, and critically from a farming perspective, growth is not as efficient.